Unsigned Heaven     Travel World     The Cheers News     Forum    

Our bodies use ancient defence mechanism to fight retrovirus    2008-07-22 09:53:26    

Washington, July 22 : A new study has found evidence that our ancestors fought against an ancient retrovirus with a defence mechanism that our bodies still use today.
A new study has found evidence that our ancestors fought against an ancient retrovirus with a defence mechanism that our bodies still use today.

Researchers at Rockefeller University and the Aaron Diamond AIDS Research Centre had earlier brought an ancient retrovirus back to life and showed it could reproduce and infect human cells.

"This is the first time that we've been able to take an ancient retrovirus and analyze how it interacts with host defense mechanisms in the laboratory in the present day," said Paul Bieniasz, who is an associate professor and head of the Laboratory of Retrovirology at Rockefeller and a scientist at the Aaron Diamond AIDS Research Centre.

The team looked at their resurrected virus, called HERV-K and tested its strength against molecules involved in human antiviral defense.

They found that human cells infected with HERV-K fought back with several antiviral proteins.

One of those proteins, called APOBEC3G, mutates virus DNA in a recognizable pattern and is one our cells use to attack modern retroviruses.

"But this is the first time it's been shown for this ancient retrovirus," said Bieniasz.

After discovering that modern human cells attacked HERV-K with this molecule, the scientists went back to look at the "fossil evidence," remnants of the virus that still remain in our genes and that they had previously used to reconstruct it.

What emerged were two copies of HERV-K that had clearly been mutated, and thus inactivated, by the APOBEC3G protein.

"We're looking at things that happened millions and millions of years ago," said co researcher and graduate student Youngnam Lee.

"But these sorts of ancient interactions may have influenced how humans are able to combat these retroviruses today. These proteins help protect us against current retroviruses," Lee added. (ANI)
© 2007 ANI

Click for more News about Health

TAGS: Health   

The Cheers NEWS is looking for new local reporters

Join The "Imagine. Create. Inspire." Conference

Get the unique insight from public relations and communications professionals from around the world. PRSA 2011 International Conference will be taking place October 15 in Orlando, USA.

Alcoholism – growing trend or lame fiction?

Alcoholism is one the addictions that is causing the most problems in today’s world. Car crashes, disturbed families, unnecessary and unpredictable violence – in very many cases too much alcohol is to blame here. Alcoholism Treatment is talked about a lot, yet most of the people going into various different treatment programs go there not because of their own will, but because they are sent there with a court order.

New Report highlights inadequacies in NHS hygiene standards
22.Jul 2008
Hospitals and Primary Care Trusts (PCT) in England have been revealed to be

Our bodies use ancient defence mechanism to fight retrovirus
22.Jul 2008
A new study has found evidence that our ancestors

Yet another way HIV fools the immune system uncovered
22.Jul 2008
Scientists at the Partners AIDS Research Center

Arthritis wonder drugs may hold key for many more diseases

Too much sleep ups ischemic risk in postmenopausal women

RComm-MTN tie-up under threat after RIL starts arbitration proceedings

Fall prevention programs cut elderly falls by 11 pct

CT scans offer cheaper diagnosis of low-risk chest pain

The Cheers magazine: About us | Contact us | The Cheers Story | Advertising
Work with The Cheers: Writers guide | Write for us | Writer application | Reporter application 
The Cheers:Terms and conditions | Privacy policy | Sponsoring | Sitemap
Sister sites: Tech Blog |  Best Auto Zine | Travel destinations by weather | Okai - critical commentary | Stock trading game | Wifi hotspots and wireless laptops | The Daily Bonk | Best Poker Zine | Business thoughts | Political commentary | Most expensive things | World News in ShortTop 10 listsPolitically incorrect blog
Listen: Online radio station
Travel World: World travel locations
Travel: Travel blogs | Travel destinations | Hotel reviews | Beer around the world
Watch: Watch series online
Trade: The Stock game | Trading competitions | Trading education
Entertainment Blogs
Entertainment blog
Copyright © 2004-2012 The Cheers magazine / Our bodies use ancient defence mechanism to fight retrovirus

web stats